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Based on currently available information, there has never been a death directly attributable to smoking pure marijuana

5 things you need to know about e-cigarettes Vaping had been seen as a healthier alternative to traditional cigarettes, but a rash of illnesses and deaths suggests that might not be true E-cigarettes have become hugely popular in the past decade but a rash of vaping-linked deaths and illnesses in the United States is feeding caution about a product, already banned in some places

MMWR (Morbidity and Mortality Weekly Report) 54(25):625-628

These risks limit near-term earnings growth

Bedaquiline does not induce or inhibit major CYP isoenzymes, namely, CYP1A2, CYP2C9, CYP2C19, or CYP2D6 at clinically relevant concentrations, minimizing the risk of CYP450-related interactions (Mesens et al., 2010)