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anxiety : A nervous reaction to events causing excessive uneasiness and apprehension

The United States Environmental Protection Agency , No

In more severe casesparticularly among children or users of high-nicotine productssymptoms can escalate to breathing difficulties, low blood pressure, paralysis, coma or even death

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Nicotine can: Constrict blood vessels and reduce circulation Increase heart rate and blood pressure Raise the risk of blood clots Interfere with hormone balance When combined with estrogen, these effects may amplify cardiovascular risks, particularly in people who use high-dose estrogen or have existing risk factors such as obesity, high blood pressure, or a history of smoking