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IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

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A Cochrane review of interventions for tobacco use cessation among people in treatment for or recovery from substance use found that offering pharmacotherapy for smoking cessation increased tobacco abstinence (risk ratio RR = 1.88, 95% CI 1.352.57), as did combined counselling and offering pharmacotherapy for smoking cessation (RR = 1.74, 95% CI 1.392.18) compared with usual care or no intervention