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Mendelian randomisation (MR) analysis In the present study, a modified Mendelian randomisation approach was performed to investigate a potential causal relationship 36,65 , in which non-pleiotropic polygenic risk scores (i.e., the valid-PRS) were established as instrument variables of randomised experiments for potential causal inference

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"And so in our study, we looked at one called NNK, which is the most potent known human carcinogen found in tobacco smoke." The Cincinnati researchers found that 70% of children living in homes with a smoker had NNK found in dust throughout their homes