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Even if your e-liquid still contains nicotine, its been shown that the effects on nicotine on the heart are similar to those of caffeine

Electronic cigarettes

Indonesia, which has one of the highest smoking rates in the world, is the only country in the Asia Pacific region that has not ratified the World Health Organization Framework Convention on Tobacco Control (WHO FCTC), while at the same time, the country witnessed a rocketing smoking rate among youth (10-18 years old) from 7.2 percent in 2013 to 9.1 percent in 2018

(2014), Date of access: 2014/04/13

The authors found their verified level of illicit trade was highest in Buffalo at 31% and in New York City at 14%