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Crucially, all of the above-mentioned factors interact with sex/gender to influence every stage of nicotine addiction (i.e., initiation, dependence, withdrawal, relapse) 59

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The word turns up in studies of Mexican-American youth slang from the 1950s onward, especially in Texas, California, and Colorado, and is associated with pachucos, also known, sometimes derisively, as zoot-suiters

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