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[27] Despite these promising secondary outcomes, the trial did not show a significant improvement in biochemically verified abstinence, which was the primary outcome
Higher doses can cause seizures, confusion, difficulty walking, and an elevated heart rate

NIHR Open Res 2025, 5:92 ( Hatsukami DK, Carroll DM

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Exposure of human skin to benzo[a]pyrene: role of CYP1A1 and aryl hydrocarbon receptor in oxidative stress generation
