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FDA is satisfied that IQOS is appropriate to promote public health and expects it to benefit the health of the population as a whole

Impaired coronary tissue plasminogen activator release is associated with coronary atherosclerosis and cigarette smoking: direct link between endothelial dysfunction and atherothrombosis

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Major players in thrombosis include hyperactive platelets, activated coagulation system, and vascular endothelium injury

Neither product qualifies as environmentally friendlytobacco cultivation requires significant resourcesbut waste profiles differ measurably