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Trends in E-Cigarette and Heated Tobacco Product use in Urban South Africa This research brief presents a summary of results from a survey which forms part of the Tobacco Control Data Initiative (TCDI) led by Development Gateway: An IREX Venture in partnership with the Research Unit on the Economics of Excisable Products and funded by the Bill and Melinda Gates Foundation

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Details of the methods and the model selection process are provided in the online supplemental file 1 and the pre-registered protocol ( For the first and second research questions (associations with cigarette consumption), the effects of the intervention (ie, standardised packaging) were modelled using a gradual change, coded 0 up to May 2017, then increasing by 1/12 each month, eventually approaching the long-term level change of 1 from June 2018 onwards