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Description

Area under crop 6000 hectares (+) Production 12.0 M.kg (+) Chemical composition Nicotine 1.3 to 2.8 per cent Reducing sugar 12.0 to 18.0 per cent Chloride 0.60 to 0.80 per cent Texture Medium to open grained

Furthermore, while the application of CRISPR/Cas9 is limited by its requirement for a specific protospacer adjacent motif (PAM) sequence featured by a 5NGG3 pattern, the discovery of Cas variants such as Cas12a (also known as Cpf1), which recognize a distinct 5TTTN3 PAM sequence, has significantly broadened the scope and versatility of genomeediting applications (Gao et al., 2017)

Similarly, a subacute lung injury of a 56-year-old man using IQOS for 2.5 years was reported 112

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