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Additionally, much of the available evidence relies on cross-sectional and observational data, which can identify associations but cannot definitively determine causality between e-cigarette use and health outcomes

Author Freddy Sitas (Associate Professor, UNSW Sydney) emphasized that the evidence is already sufficiently consistent to support concern, even though definitive long-term epidemiological data will take decades to accumulate

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All these inflammatory indices were significantly higher in the mice with M-CS exposure than in those with Non-M-CS exposure (Figure 3)