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The antimicrobial effects derive primarily from sage's volatile oils, especially 1,8-cineole (eucalyptol) which can comprise a significant portion of white sage essential oil.6 This compound shows activity against numerous bacteria including Staphylococcus aureus, Escherichia coli, and various respiratory pathogens

If one considers a single bogie "up close", it resembles a small railcar with axles at either end

People believed snuff had valuable medicinal properties, which added a powerful impetus to its consumption

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