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The calculator just needs the total floor area

This makes nicotine pouches different from cigarettes or vaping products because there is no smoke or vapor involved

Despite the obvious biologic plausibility, the lack of consistent epidemiological evidence might be due to methodological issues including lack of cohort follow-up time into older adulthood (when lung cancer usually becomes clinically manifest), small sample sizes, selection and recall biases, and lack of adjustment for tobacco use in the statistical modeling

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