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His company, Golden Dragon Holdings filed for a patent and changed its name to Ruyan, meaning resembling smoking. Later that year, the devices went on the market in China

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Keywords: animal models, cardiac function, cardiopulmonary physiology, clinical research, e-cigarette, inflammation, lung function, nicotine, vaping Graphical Abstract Abstract figure legend Data across both human and animal studies demonstrate that daily inhalation of e-cigarette or vaping device aerosols on a chronic basis will cause significant cardiopulmonary disease

Winston stepped down after 33 years as title sponsor of NASCAR's championship series and was replaced by Nextel