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These levels are very similar to those produced by cigarette smoking, suggesting that a learning curve effect has to be taken into account when discussing clinical studies with E-cigs

The nicotine content is 1.5% (15mg/g) which breaks down to 13.20mg/portion

In fact, rs887200 was associated with four of the five ND phenotypes, suggesting that COMT may underpin the early development of ND in novice smokers

However, more recent probability-based online samples,[25] lessen such concerns

However, the odds ratios associated with these were modest compared to that of EC use, suggesting that EC use may pose increased risk for coughing and wheezing among never-smoking young adults