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Despite these limitations, this study demonstrated the safety and feasibility of two regimens and provides preliminary data to inform the design of a larger RCT of CSD + CHG, and TA + SPU (with TA at insertion only) versus standard care (used in this study), to improve PICC outcomes

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The primary outcome was PICC failure, a composite of PICC removal for local infection, catheter-associated bloodstream infection, dislodgement, occlusion, and/or catheter fracture