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Copper ions (Cu 2+ /Cu) damage membranes, denatures proteins, binds nucleic acids, and elevates intracellular ROS, producing broad-spectrum activity including against resistant strains 218,219

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The World Anti-Doping Agency has banned these compounds, noting they lack approval from any health regulatory authority and are intended only as research tools

Morphological analysis of hepatocellular layers indicated the occurrence of marked toxicity after treatment with TVX concentrations 10 M for 7 days in accordance with vascular injury

Borthakur G , Lin E, Jain N, Estey EE, Cortes JE, O'Brien S, Faderl S, Ravandi F, Pierce S, Kantarjian H