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a black box warning for thyroid tumors applies

Chen, L., Jia, L., Zhang, Q., Zhou, X., Liu, Z., Li, B., et al., Anaerobe , 2017, vol

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Although p53 induced apoptosis via PUMA and NOXA and cell senescence via p21 play critical roles in preventing cells from malignant transformation, these two mechanisms are dispensable for p53-mediated suppression of spontaneous tumour development

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