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The published data show that estrogen-like molecules can mimic or block endogenous estrogens biological effects through a series of non-genomic responses (Park et al., 2012

Int., 2017, 99, 7886 CrossRef CAS

Furthermore, CHAC1 induction is directly suppressed by m 6 A methylation

Identification and characterization of potent, selective and metabolically stable IKKbeta inhibitor

These approaches measure effects across a range of biological pathways simultaneously and can be used to investigate a chemicals mode of action, predict toxicological effects, characterize dose response relationships, and understand species relevance
