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Description
The mitochondrial AST enzyme is encoded by the GOT2 gene which is located on chromosome 16q21 and is composed of 10 exons that generate two alternatively spliced mRNAs encoding precursor proteins of 430 amino acids (isoform 1) and 387 amino acids (isoform 2)
This study only followed patients for 8 weeks
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Substances with long half-lives that accumulate in tissues over time present different risk profiles than those rapidly cleared
