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Sterility is critical

Tap water is never acceptable

Adults who are lean, experience rapid progression to insulin requirement, or test positive for islet autoantibodies may have latent autoimmune diabetes in adults (LADA), which behaves more like Type 1 than Type 2 and eventually requires insulin

10.1089/ars.2016.6755 36 GiulianteR.SartiniD.BacchettiT.RocchettiR.KltingI.PolidoriC.et al (2015)

Relief from knee gel injections is not immediateit typically takes several weeks to notice improvement
