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IL-6 is often used as a marker because of its central role in triggering and sustaining the inflammatory response (Kany et al
doi: 10.1158/0008-5472.CAN-12-1076
doi: 10.1016/bs.ctdb.2020.11.002 56
It is noticeable that there is less reliance on only Phase 1 routes of metabolism in this set of drugs, compared to the past two years (Figure 1)
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