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Similarly, no significant changes in LINE-1 and Alu methylation among female nurses was observed, although several gene-specific hypomethylation effects to the estrogen receptor gene ESR1 (associated with heightened estrogen sensitivity), to the tumor suppressor genes TP53 and BRCA1 (indicating possible disruption in cell cycle regulation and DNA repair mechanisms) were reported

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Zinc released during neurotransmission was found to bind to amyloid- peptides, accelerating the assembly of amyloid- into oligomers that impair synaptic function

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Additionally, they show elevated pathways related to cell division and growth mediated by cyclins and cell cycle regulators
