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Cognitive decline and neuropsychiatric symptoms The degeneration of dopaminergic neurons in the basal ganglia disrupts executive functions, leading to difficulties in planning, problem-solving, and multitasking

[DOI] [PubMed] [Google Scholar] 15.Zhang J, Xiong C, Ying J, Wang W, Hruby VJ

Di Emidio, G

These measures are invaluable for screening, monitoring, and proof-of-concept, but a change in an imaging fat fraction or a blood panel is a surrogate: it supports, but does not by itself establish, the biopsy endpoints regulators require
Raizman, J