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Decreased expression in hypothalamic neurons results in abnormal physiological stress response, hyper-aggressiveness, and obesity (86)
It should be noted that a related molecule, ()-physostigmine (5), can cross the bloodbrain barrier
Previous studies showed that mice lacking LXR were unable to induce the transcription of gene encoding Cyp7a, confirming the important role of LXR in dietary cholesterol metabolism (Peet et al., 1998
J Hand Surg Glob Online
