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Description
Liraglutide, an agonist of GLP-1R, can increase acetyl-CoA carboxylase (ACC) phosphorylation through activation of AMPK, which in turn attenuates Erastin- or RSL3-induced cellular ferroptosis in the presence of high glucose, suggesting that Liraglutide ameliorates T2DM-associated NAFLD by inhibiting ferroptosis through activation of AMPK/ACC signaling [157]

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Interestingly, given that BPC 157 by itself does not induce any behavioral change as mentioned, we identified a similar overexpression of the genes in the healthy rats treated with the ketamine (Nos1, Nos2, Plcg1, Prkcg, Ptgs2, and Ptk2) and in the BPC 157 (Nos1, Nos2, Plcg1, Prkcg, and Ptk2)

C., Chan J., Chang C
May 2009, Vol 18(1)p
