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Notably, Fer-1 and Nec-1 prevented OGD-induced cell death, while inhibitor 3-MA and Z-VAD-FMK did not (Fig

As proteins with a sulfydryl group are often target of oxidation (SH groups can be easily oxidized), small-molecular-weight thiols are potent scavengers

The antioxidant effects were demonstrated in vitro by a decrease in ROS and nitric oxide levels and the formulations preventive effect in decreasing the total thiol content

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(2019) 5:CD001287
