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In the following sections, the main targeting vectors are considered for monotherapy and chemical modification of therapeutic drugs or nanocarriers that can provide receptor- and carrier-mediated delivery of drugs into brain tumors

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The naturally occurring ligands for PPAR- are leukotriene B 4 (LTB 4 , see the Eicosanoid Metabolism: Prostaglandins, Thromboxanes, Leukotrienes, and Lipoxins page), unsaturated fatty acids and oxidized components of VLDL and LDL