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Mean triglycerides were 2844 mg/dL (normal limits 16252)

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Kieseier, and Alfred Sandrock are employees of and hold stock/stock options in Biogen.

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"TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth"

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however, it is not known whether this occurs at clinically relevant doses in humans

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[Crossref] Chang SY, Di A, Naren AP, Palfrey HC, Kirk KL, et al

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