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Furthermore, the more recent observational data suggesting that the combination of high folate and low vitamin B-12 is associated with the worsening of both clinical outcomes and elevations in functional biomarkers of vitamin B-12 (23, 40, 41) imply that depletion of holoTC is attained even without stimulating hematopoiesis

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[DOI] [PubMed] [Google Scholar] 32.Lucas R, Warner TD, Vojnovic I, Mitchell JA