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For instance, the Michael acceptor methylene quinuclidinone, the active form of APR-246, was shown to be a potent and direct inhibitor of both TXNRD1 and Glutaredoxin-1 (GRX1) by reacting with the selenocysteine group in both enzymes

Yaghi, S

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the AnglV analogue treatment-induced increase in spine head width suggests facilitated neurotransmission

in Bancrofts Theory and Practice of Histological Techniques 3768 (Elsevier, 2013)
