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Severe, long-standing damage may take longer or may be permanent, which is why early treatment matters
Kern JK et al
PMID: 27 DantzlerW
T-cell proliferation involving the CD28 pathway is associated with cyclosporine-resistant interleukin 2 gene expression
Additionally, a study found that neuronal release of D-serine modulates N-methyl-D-aspartate receptor (NMDAR) function, and some of the D-serine produced by neurons might be transported into astrocytes and metabolized via the peroxisomal D-amino acid oxidase (DAO) enzyme (Wolosker and Radzishevsky, 2013)
