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Indeed, subsequent experiments showed that longer treatments with either PIPLC or monoclonal antibodies to PrP C can cure infected cell cultures [Peretz 2001, Enari 2001], suggesting that, at least in ScN2a cells, re-internalized PrP C is the predominant substrate for conversion to PrP Sc , with little or no contribution from nascent PrP just coming up the secretory pathway
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Nature 436 , 193200 (2005)
"An involvement of acetylcholine in object discrimination learning and memory in the marmoset"
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