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Diagnosis and management of glutaric aciduria type I--revised recommendations

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Another meta-analysis of four randomized, placebo-controlled trials found evidence of a reduction in fasting plasma glucose concentration and no improvement of glycated hemoglobin concentration in subjects with type 2 diabetes mellitus supplemented with acetyl-L-carnitine (ALCAR) (44)

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Thus, repeated intravenous L-carnitine supplementation may produce a greater increase the total carnitine concentration in skeletal muscle than oral L-carnitine during the modified fasting period