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Isolation of a new gene GS2 (DXS1283E) from a CpG island between STS and KAL1 on xp22.3

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Therefore, the problem that the agents successful in pre-clinical experimental autoimmune encephalitis trials, were either less effective in patients, worsened disease or caused unexpected, severe adverse events (60), may be at least partly solved with the more suited cuprizone model that reflects a toxic experimental model (12)

Caution is recommended in individuals with seizure disorders, as increased frequency or severity of seizures has been reported during therapy