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The Candida pathogenic species complex

BMC Health Serv Res

The structure of a zeta class glutathione S -transferase from A

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Interferon- Interferon- (IFN-) is mainly involved in the regulation of inflammatory immune responses, and levels are elevated in the intestinal mucosa in patients with IBD.39 Recent studies have also demonstrated that IFN- increases paracellular permeability in intestinal epithelial cells through the redistribution and expression of TJ proteins and the rearrangement of the actin cytoskeleton.40 Thus, IFN- increases actinmyosin contractility in a Rho-associated kinase-dependent manner and induces TJ protein internalization, resulting in intestinal TJ disruption