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Factor 3: Balance convenience against precision

[DOI] [PubMed] [Google Scholar] 7.Jones M.R., Urits I., Wolf J., Corrigan D., Colburn L., Peterson E., Williamson A., Viswanath O

SIRT1 is also known as the "longevity gene" because of its role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer

I live in a little country town, and that is the only store in my area that carries any in the methyl form

Most practitioners recommend starting at 250-300 mcg daily to assess tolerance, then potentially increasing to 400-500 mcg if initial response is suboptimal and no side effects occur