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Science (2021) 4

Effects of Oral Glutathione Supplementation on Systemic Oxidative Stress Biomarkers in Human Volunteers

7.3 Microbiome-based targeted therapeutics Metabolites resulting from gut dysbiosis (e.g., decreased SCFAs, increased BCAAs) and endotoxin (LPS) translocation exacerbate pulmonary inflammation via the gut-lung axis
Moreover, the largest clinical trials included in the meta-analysisand, in consequence, those with more power in the analysisused vitamins E and C, i.e., supplements without proven beneficial effects

2022;323:E2E7