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parkeri in macrophages by guanylate binding proteins (GBPs) causes caspase 11 inflammasome activation and pyroptosis 43
15 As a transcription factor, c-Myc directly binds to DNA at E-box domains (CACGTG or similar sequences) as a heterodimer with one of its bHLHLZ interacting partners, Max being the most common

In response to these changes, in 2020 an international group of experts proposed a new classification, termed metabolic dysfunction-associated fatty liver disease (MAFLD) [16, 17]
