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Description
Because clomiphene citrate and tamoxifen increase testicular function by increasing gonadotropin signaling, these drugs are sometimes used empirically to treat idiopathic male infertility

There is no official link between standard B12 supplementation and serious adverse effects in individuals with normal kidney and liver function

This approach stems from the understanding that biological systems often respond to subtle stimulation in ways that stronger interventions cannot replicate

According to NICE guidance and standard UK clinical practice, patients with confirmed B12 deficiency and neurological symptoms typically require initial treatment with hydroxocobalamin injections

Front Neurosci 15:663053
