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Senescent but not young RBC, as obtained by density separation, are phagocytosed by macrophages, while phagocytosis of in vitro aged RBC requires opsonization with autologous IgG

Anabel AS, Eduardo PC, Pedro Antonio HC, Carlos SM, Juana NM, Honorio TA, et al

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This experimental evidence supports the notion that GlyT1 inhibition such as NFPS, SSR504734, M22, sarcosine, and LY2365109 exhibits promising anticonvulsant effects in several epilepsy models (Table 2)
