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High-throughput profiling of serum exosomal microRNAs may allow dynamic and noninvasive monitoring of treatment response, immune state, and maternal-fetal interface homeostasis (98, 99)

doi: 10.1172/JCI68782 153 KawaseMSuwaRSugimotoSKakizakiMKumeYOkabeHet al

doi: 10.1038/s41392-024-01772-w

Nevertheless, these systems frequently generate proteins in the form of inclusion bodies, requiring extensive and expensive downstream processing steps such as solubilization, refolding, and chromatography

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