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Massey RL, Kim HK, Abdi S

10.1016/j.bbamcr.2022.119417 Biochim

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One study indicated that 500 mg daily resulted in a visible reduction in melanin indices after just four weeks of consistent use

According to the authors, other reported complications of coffee enemas include: thermal burns from heated coffee enemas stricture, which is an area of narrowing within the intestines bowel perforation Considerations Before considering a coffee enema, people should familiarize themselves with the potential risks of the procedure
