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Abnormally increased interaction of FUS/TLS with SMN might affect its normal nuclear and/or cytoplasmic dynamics and lead to Gem body reduction and dysregulation of snRNA levels, a potential common mechanism of SMN deficiency in SMA

the column was washed first with 1.0 bed volume of loading buffer at a flow rate of 5 ml/min
The results showed that CD31 + -SMA + cells were prominent in the coronary artery intima in the PD-1 inhibitor group, whereas such double-positive cells were rarely detectable in the control group (Figure 5A), indicating EndMT occurred in PD-1 inhibitor-treated heart
