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Study participants were randomized to receive placebo, 1 or 3 g GPLC per day

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Activating alpha7 nicotinic acetylcholine receptor inhibits NLRP3 inflammasome through regulation of beta-arrestin-1

SK channels are solely activated by transient elevations of intracellular Ca 2+ and form functional heteromeric complexes with calmodulin, that acts as a high-affinity Ca 2+ sensor (Lee et al., 2003
