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Even treatment with recommended doses may cause hyperkalemia when trimethoprim is administered to patients with underlying disorders of potassium metabolism, with renal insufficiency, or if drugs known to induce hyperkalemia are given concomitantly

ATX code V03AB32 Indications for use prevention of neurotoxicity during chemotherapy with cisplatin or other related compounds List of information required before use Contraindications hypersensitivity to the active substances or to any of the excipients Necessary precautions for use In case of adverse reactions during intravenous administration, use of the drug should be discontinued immediately

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The distinction between malignant and benign phenotypes was established by the presence of lower levels of free cysteine in the plasma of women with benign tumours

Reported or potential effects include: Hypoglycemia: IGF-1 enhances glucose uptake by muscles, which can occasionally lead to transient low blood sugar, especially when fasting or undernourished