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VIP differentially induces histamine release from mast cells in that peritoneal mast cells respond to VIP more than intestinal mucosal mast cells 47 , likely corresponding to the VPAC1 activation on mast cells

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However, at the lowest concentration of epitalon (0.1ug/ml), we observed a decrease in telomere length for 21NT, and a lower rate of telomere elongation for BT474