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Structure of bacterial glutathione-S-transferase maleyl pyruvate isomerase and implications for mechanism of isomerisation

179 Interestingly, ROCK inhibitor was also shown to inhibit lipopolysaccharide (LPS)-induced MLC phosphorylation and occludin downregulation

Hyperthyroidism and Liver Dysfunction: A Review of a Common Comorbidity

The Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus-Thrombolysis in Myocardial Infarction (SAVOR-TIMI) 53 trial assessed the impact of saxagliptin on cardiovascular outcomes and reported an increase in rates of hospitalisation for HF with no impact on ischaemic events.85 Further clinical trials have been conducted, reporting no increased risk of HF or other cardiac outcomes,86 however, these trials still report no improvement