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doi: 10.1084/jem.20041611 280 TapiasV.JainuddinS.AhujaM.StackC.ElipenahliC.VignisseJ.et al

A call for accessible tools to unlock single-cell immunometabolism research

In prostate and lung adenocarcinomas, loss of the Numb/Parkin pathway results in metabolic reprogramming marked by a significant increase in lactate generation, which in turn causes an increase in histone Kla and the activation of the transcription of genes linked to neuroendocrine function

Table 1 Summary of human clinical trials with CAR-T cells in rheumatic autoimmune diseases