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Halder J, Mahanty R, Rajwar TK, Rai VK, Kar B, Ghosh G, et al

SREBP-1c is positively regulated by insulin and negatively by AMPK and promotes enzymes, i.e., acetyl-CoA carboxylase (ACC1) and fatty acid synthase (FAS), which are involved in de novo fatty acid synthesis [85,86]

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iPSC-derived human liver organoid culture The iHLOs at various developmental stages were obtained from 3Dnamics, Inc

Zhou M, Zhang R, Huang M, Lu W, Song S, Melancon MP, et al